The power of local therapy in superficial bacterial infections- part 2

67668506_2745972975432468_1475995593221341184_nDr Spas Spasov

Veterinary Center Dr Antonov

Varna, Bulgaria

 

Sandra is a French bulldog whose case I have been following  for 2 years.

Sandra is regularly vaccinated and with regular tick and flea treatmen and dewormig as well .

 

When we first met, Sandra  was prescribed 2 mg of Prednisolone per kg in the morning and evening.

There were already 2-3 diets with hypoallergenic food with no results .

When the dog is on Prednisolone is very good, with no symptoms.

 

Sandra has been on immunotherapy for two years and during this time there are a total of 3-4 exacerbated periods with superficial bacterial infection.86731524_2593062557606841_6481170903102128128_n 86796564_540897716551707_1088806477625294848_n

To control these infections we tried various antibacterial shampoos and the ONLY systemic antibiotic we used was amoxicillin with clavulonic acid (at least one month ingestion)86654192_3849015221805694_8360675259283668992_n 86671200_2685748064865626_3817080252207726592_n 86696362_2218223128473460_5054249941212332032_n 86697202_485388832135765_3554367668330954752_n

86648294_214183006375305_3623894315450761216_nDuring immunotherapy, Sandra takes 1/4 of Prednisolone at 5 mg every 36 hours (Sandra weights about 15 kg throughout the therapy).

For two years, Sandra was very good, and controlling the pyoderma was relatively easy without changing the doses of immunotherapy and without changing the dose of Prednisolone.

The last case of bacterial infection was the beginning of November 2019.86696316_183578386233461_4810920583397113856_n 86702696_191563688606644_4592023430513033216_n

We began the scheme with Chloroxiderm and Amoxicillin with clavulonic acid.

10 days later, it had no effect, even the opposite.

Sandra’s skin was flushed with pustules, color and intense itching.

 

We did cytology, bacteriology and antibiogram.

The results (Staph. intermedius ) were completely resistant to 15 types of antibiotic from different groups.

The only antibiotic that worked was Rifampim, which is a strategic antibiotic in human medicine and we decided not to use.

Sandra’s improvement has been much slower and in the last few months we have changed several different regimens of local therapy.

Peptive Shampoo & Foam, Duoxo tampons & duoxo spo on  (First Month Every Day)

Omega 3 and 6 fatty acids, Chloroxiderm shampoo, Duxo pyo shampoo and foam (second month every day)

Since the beginning of January, Sandra has been on Peptive again with a bath twice a week and a hermitra spray.

The itching has decreased to normal, there are no new pustules and the hair is gradually recovering.

In conclusion, every time we use an antibiotic for systemic therapy or topical therapy, we should think very carefully about all the possible options because resistance is one of the greatest problems of our future.

Diagnosis :

Atopic dermatitis

Superfitial pyodermia