Dr Spas Spasov
Veterinary Center Dr Antonov
Varna, Bulgaria
1.Case History
The cat is 3 y old ,female non castrated ,regular vaccinated ,tick and flea treatment with advocate .
The problem of the cat begane one year ago in with claw bed problems ( yellow puss from there ) ,the cat have also lesions on its ears and nose .
In other clinic in other country my other vet is start with antibiotics and steroid therapy (improvement for few months )
2.Clinical presentation
Paronychia, crusty and scaly nose ,crusty and scaly ears, pruritus, painful walking no other skin lesions and symptoms .
3.Differential diagnoses
Fungal infection
Pemphigus Foliaceus
Demodecosis
Pyodermia
Allergy
4.Diagnostic approach
CBC and Biochemistry –Unremarkable
DTM – Negative
Skin scrape and scotch tape – Negative
Cytology – Neutrophils ,bacteria ( cocci ) and acantholytic cells .
Microbiology ( Staff .aureus )
5.Therapeutic approach
14 days Amoxicillin and clavulanic acid and topical therapy with chlorexiderm 4 % ( almost no improvement)
New cytology – Normal neutrophils and acantholytic cells (no bacteria )
Punch biopsy of nail bed .
Pathohistologi report :
Report – Histopathology release date: 23.02.2021
Description
- There were examined 5 representative sections (Hematoxylin-Eosin stain) from each sample, showing
similar histopathological appearance:
Epidermis with orthokeratotic hyperkeratosis, spongiosis and crusts (composed of acantholitic cells and
neutrophils). Superfcial and deep dermis show oedema, perivasculary to diffuse infammatory infltrate
with eosinophils, few mast cells, few lymphocytes and plasma cells. The hair follicles are in telogen and
catagen phases. The glands (apocrine and sebaceous glands) are well represented, without any
changes. There is no evidence of neoplasia, parasites or fungi in the examined sections.
- There were examined 5 representative sections (PAS stain – fungi) from each sample, showing similar
histopathological appearance:
NEGATIVE
Interpretation
The histopathological appearance is consistent with hyperkeratosis, suppurative epidermitis, chronicactive dermatitis with eosinophilic component (allergic component).
Comments
The histopathological aspects are suggestive for pemphigus foliaceus. Suspicion is confirmed.
Therapy :
Prednisolon tablets 2 mg per kg twice a day for 14 days then slowly reduce dose to a minimum working dosage .
6 moths later the cat was perfect then ,the owners call regular just to tell us that everything is ok .
Diagnose :
Pemphigus foliaceus
