Cutaneous neutrophilic panniculitis and vasculitis in a shar-pei associated with autoinflammatory disease

Okan-KahramanDr. Okan Kahraman, DVM

İkon veterinary clinic

İstanbul/ turkey



A 5-year-old neutered male Shar-Pei presented to the dermatology service with swelling and ulcerative crusted lesions on the flanks and chest.

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The patient was clinically diagnosed with Shar-Pei Autoinflammatory Disease (SPAID), characterized by recurrent episodes of fever and lethargy occurring once or twice annually, resolving spontaneously or with the use of non-steroidal anti-inflammatory drugs (NSAIDs).


Cytological examination

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Cytological examination of the skin lesion revealed a neutrophilic infiltrate with infectious agents (coc bacteri) , compatible with neutrophilic dermatitis-panniculitis.

Treatment and outcome:

Treatment was 1mg/kg prednisolon oral tablets (24h) 10 days than reduce dosis

Rilexine (virbac) 300 mg twice Daily 15 days

Antibacterial shampoo weekly

The neutrophilic panniculitis and vasculitis observed in this case responded well to anti-inflammatory corticosteroid therapy, implying

an underlying autoinflammatory condition as the etiology of the skin lesions.


1 weeks later

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2 moths later

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okan 2

Dr Okan Kahraman

Case Presentation


Vet.Okan KAHRAMAN Greenpet Veterinary Clinic     İstanbul/Turkey




Signalament and History

. 3month unvaccinated female cat

. The cat licking the affected foot pads also smelling bad at foot pads sometimes lamess were observed



Pysical Examination

.All foot pads were affected

.Swollen,soft,ulcerated/erosions (also contaminated with bacteria )

.and some of them were paintful while pysical examination espacially whish one has ulcerated

.vital signs were completly well

okan 1

Picture 1

.photos (include each foot pads) ( Picure 1)


Laboratory results

. Just Leucocystosis other parameters were okay. FIV And FelV test was (-)

Differential Diagnosis.Plasma Cell Pododermatitis.FIV ,FelV.Autoimmune Dermatoses (pemhigus complex,lupus eryt.).Neoplasia


Diagnosis and Treatment.

Feline plasma cell pododermatitis .

prednisolon 1mg/kg X 2 PO (3 day ) after 3.

Day 4mg/kg Metilprednisolon asetat

S.c.cefovesin (convenia ) 8mg/kg S.C.

clindamycin 15mg/kg X 2 PO (5 day ) .


okan 3

Picture 2

After 10 days later Photos( Picture 2)